Found 9 matching trials
A Study to Assess the Reaction of Body for Four Different Formulations of AZD9977 (Part A) and Influence of Food and Lower Dose of a Selected Formulation (Part B) in Healthy Male Subjects PHASE1 AZD9977 is an oral, selective mineralocorticoid receptor (MR) modulator. AZ...
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A Single Oral Dose Study to Evaluate Four Different Formulations of AZD9977 and the Effect of Food in Healthy Male Subjects PHASE1 This study will evaluate pharmacokinetics (PK) of four different formulatio...
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A Study to Compare the Pharmacokinetics of Different Formulations of AZD9977 and the Influence of Food in Healthy Male Subjects PHASE1 This is an open-label, randomized, cross over single oral dose study to com...
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Study to Investigate the Effect of Hepatic Impairment on the Pharmacokinetics, Safety, and Tolerability of Balcinrenone PHASE1 This study will evaluate the pharmacokinetics (PK), safety, and tolerabilit...
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Study in HFpEF Patients to Compare the Effect of AZD9977 and Spironolactone on Serum Potassium PHASE1 This is a Phase I, Multicentre study to Compare the Effect of AZD9977 and S...
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A Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD9977 After Single Ascending Doses to Healthy Males PHASE1 This study will be a randomized, single-blind, placebo-controlled first-in-...
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A Phase 1 Study to Assess the Pharmacokinetics of AZD9977 Administered Alone and in Combination With Itraconazole in Healthy Volunteers PHASE1 This is an open-label, non-randomized, fixed sequence study conducted at a ...
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Absolute Bioavailability and ADME Study of [14C]AZD9977 in Healthy Male Subjects PHASE1 Study to Assess the Absorption, Metabolism, and Excretion of \[14C\]AZD9977...
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Study to Assess the Bioavailability of Different Formulations of AZD9977 and Dapagliflozin and Influence of Food in Selected Formulations in Healthy Volunteers PHASE1 The primary purpose of the study is to evaluate relative bioavailability of...
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